Xylo-oligosaccharides Inhibit Enzymatic Hydrolysis by Influencing Enzymatic Activity of Cellulase from Penicillium oxalicum

Xylo-oligosaccharides, as the important intermediates of hemicellulose degradation, widely exist in hydrolysate from pretreatment and enzymatic hydrolysis of lignocellulose. This study showed that xylo-oligosaccharides largely reduced the efficiency of cellulose hydrolysis, but this inhibition cannot be effectively relieved by increasing loading of cellulose substrate or cellulase. Xylo-oligosaccharides largely suppressed enzymatic activities of...