Identification of enhanced IFN-γ signaling in polyarticular juvenile idiopathic arthritis with mass cytometry
Abstract
Polyarticular juvenile idiopathic arthritis (JIA) is among the most challenging of the JIA subtypes to treat. Even with current biologic therapies, the disease remains difficult to control in a substantial subset of patients, highlighting the need for new therapies. The aim of this study was to use the high dimensionality afforded by mass cytometry with phospho-specific antibodies to delineate signaling abnormalities in immune cells from...
Paper Details
Title
Identification of enhanced IFN-γ signaling in polyarticular juvenile idiopathic arthritis with mass cytometry
Published Date
Aug 9, 2018
Journal
Volume
3
Issue
15
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