In vitro and in vivo evaluation of a posaconazole-sulfobutyl ether-β -cyclodextrin inclusion complex
Abstract
Posaconazole (PCZ) is a triazole antifungal agent with an extended spectrum of antifungal activity. It is approved for the prophylaxis of invasive fungal infections in patients with neutropenia or in hematopoietic stem cell transplant recipients undergoing high-dose immunosuppressive therapy for graft-vs-host disease, and for the treatment of fungal infections. However, its pharmacological effects are severely limited owing to its poor...
Paper Details
Title
In vitro and in vivo evaluation of a posaconazole-sulfobutyl ether-β -cyclodextrin inclusion complex
Published Date
Sep 5, 2018
Journal
Volume
32
Issue
12
Pages
e4364 - e4364
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Notes
History