Polyunsaturated fatty acids for the primary and secondary prevention of cardiovascular disease

Evidence on the health effects of total polyunsaturated fatty acids (PUFA) is equivocal. Fish oils are rich in omega-3 PUFA and plant oils in omega-6 PUFA. Evidence suggests that increasing PUFA-rich foods, supplements or supplemented foods can reduce serum cholesterol, but may increase body weight, so overall cardiovascular effects are unclear.To assess effects of increasing total PUFA intake on cardiovascular disease and all-cause mortality,...