Targeted DNA and RNA Sequencing of Paired Urothelial and Squamous Bladder Cancers Reveals Discordant Genomic and Transcriptomic Events and Unique Therapeutic Implications.

Volume: 74, Issue: 6, Pages: 741 - 753
Published: Dec 1, 2018
Abstract
null null Background null Integrated molecular profiling has identified intrinsic expression-based bladder cancer molecular subtypes. Despite frequent histological diversity, robustness of subtypes in paired conventional (urothelial) and squamous components of the same bladder tumor has not been reported. null null null Objective null To assess the impact of histological heterogeneity on expression-based bladder cancer subtypes. null null null...
Paper Details
Title
Targeted DNA and RNA Sequencing of Paired Urothelial and Squamous Bladder Cancers Reveals Discordant Genomic and Transcriptomic Events and Unique Therapeutic Implications.
Published Date
Dec 1, 2018
Volume
74
Issue
6
Pages
741 - 753
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