Expression Profile of LGR5 and Its Prognostic Significance in Colorectal Cancer Progression
Volume: 188, Issue: 10, Pages: 2236 - 2250
Published: Oct 1, 2018
Abstract
We investigated the expression profile of leucine-rich, repeat-containing, G-protein–coupled receptor 5 (LGR5) during colorectal cancer (CRC) progression and determined the prognostic impact of LGR5 in a large cohort of CRC samples. LGR5 expression was higher in CRCs than in normal mucosa, and was not associated with other cancer stem cell markers. LGR5 positivity was observed in 68% of 788 CRCs and was positively correlated with older age,...
Paper Details
Title
Expression Profile of LGR5 and Its Prognostic Significance in Colorectal Cancer Progression
Published Date
Oct 1, 2018
Volume
188
Issue
10
Pages
2236 - 2250
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