Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells
Volume: 24, Issue: 28, Pages: 3120 - 3129
Published: Jul 28, 2018
Abstract
To evaluate the influence of hyperglycemia on the progression of autoimmune pancreatitis.We induced hyperglycemia by repetitive intraperitoneal (ip) injection of 50 mg/kg streptozotocin in MRL/MpJ mice, which develop autoimmune pancreatitis due to a genetic predisposition. We compared the extent of inflammation (histological score, CD3+ lymphocytes, CD8+ T-cells, CD4+ T-cells, Foxp3+ T-helper cells) in the pancreas of hyperglycemic and...
Paper Details
Title
Impact of hyperglycemia on autoimmune pancreatitis and regulatory T-cells
Published Date
Jul 28, 2018
Volume
24
Issue
28
Pages
3120 - 3129
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