L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury
Abstract
There is a need for pharmaceutical agents that can reduce neuronal loss and improve functional deficits following traumatic brain injury (TBI). Previous research suggests that oxidative stress and mitochondrial dysfunction play a major role in neuronal damage after TBI. Therefore, this study aimed to investigate two drugs known to have antioxidant effects, L-carnitine and exendin-4, in rats with moderate contusive TBI. L-carnitine (1.5 mM in...
Paper Details
Title
L-Carnitine and extendin-4 improve outcomes following moderate brain contusion injury
Published Date
Jul 25, 2018
Journal
Volume
8
Issue
1
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