Thermal proteome profiling in bacteria: probing protein state in vivo
Abstract
null Increasing antibiotic resistance urges for new technologies for studying microbes and antimicrobial mechanism of action. We adapted thermal proteome profiling (TPP) to probe the thermostability of null Escherichia coli null proteins null in vivo . null E. coli null had a more thermostable proteome than human cells, with protein thermostability depending on subcellular location—forming a high‐to‐low gradient from the cell surface to the...
Paper Details
Title
Thermal proteome profiling in bacteria: probing protein state in vivo
Published Date
Jul 1, 2018
Journal
Volume
14
Issue
7
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