Immunoglobulin E

Antibody

Immunology

Allergy

Asthma

Vernal keratoconjunctivitis

Allergic response

Atopic dermatitis

Allergic inflammation

Allergic conjunctivitis

Chronic rhinosinusitis

Allergic asthma

Medicine

Immune system

Molecules

Allergic diseases, which include asthma, allergic rhinitis (AR), chronic rhinosinusitis (CRS), atopic dermatitis (AD), food allergy (FA), allergic keratoconjunctivitis, seriously affect the quality of life of people all over the world. Recently, interleukin-33 (IL-33) has been found to play an important role in these refractory disorders, mainly by inducing T helper (Th) 2 immune responses. This article reviews the mobilization and biological function of IL-33 in allergic disorders, providing novel insights for addressing these hypersensitive conditions.

Interleukin-33: Its Emerging Role in Allergic Diseases