Effects of Sacubitril/Valsartan Versus Irbesartan in Patients With Chronic Kidney Disease
Abstract
Background: Sacubitril/valsartan reduces the risk of cardiovascular mortality among patients with heart failure with reduced ejection fraction, but its effects on kidney function and cardiac biomarkers in people with moderate to severe chronic kidney disease are unknown. Methods: The UK HARP-III trial (United Kingdom Heart and Renal Protection-III), a randomized double-blind trial, included 414 participants with an estimated glomerular...
Paper Details
Title
Effects of Sacubitril/Valsartan Versus Irbesartan in Patients With Chronic Kidney Disease
Published Date
Oct 9, 2018
Journal
Volume
138
Issue
15
Pages
1505 - 1514
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