Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes
Abstract
Obesity and its metabolic complications are characterized by subclinical systemic and tissue inflammation. In rodent models of obesity, inflammation and metabolic impairments are linked with intestinal barrier damage. However, whether intestinal permeability is altered in human obesity remains to be investigated. In a cohort of 122 severely obese and non‐obese patients, we analyzed intestinal barrier function combining in vivo and ex vivo...
Paper Details
Title
Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes
Published Date
Aug 28, 2018
Journal
Volume
246
Issue
2
Pages
217 - 230
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Notes
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