Polymeric Nanoparticles Limit the Collective Migration of Cellular Aggregates
Abstract
Controlling the propagation of primary tumors is fundamental to avoiding the epithelial to mesenchymal transition process leading to the dissemination and seeding of tumor cells throughout the body. Here we demonstrate that nanoparticles (NPs) limit the propagation of cell aggregates of CT26 murine carcinoma cells used as tumor models. The spreading behavior of these aggregates incubated with NPs is studied on fibronectin-coated substrates. The...
Paper Details
Title
Polymeric Nanoparticles Limit the Collective Migration of Cellular Aggregates
Published Date
Jul 5, 2018
Journal
Volume
35
Issue
23
Pages
7396 - 7404
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