Volumetric, Nanoscale Optical Imaging of Mouse and Human Kidney via Expansion Microscopy
Abstract
Although light microscopy is a powerful tool for the assessment of kidney physiology and pathology, it has traditionally been unable to resolve structures separated by less than the ~250 nm diffraction limit of visible light. Here, we report on the optimization, validation, and application of a recently developed super-resolution fluorescence microscopy method, called expansion microscopy (ExM), for volumetric interrogation of mouse and human...
Paper Details
Title
Volumetric, Nanoscale Optical Imaging of Mouse and Human Kidney via Expansion Microscopy
Published Date
Jul 10, 2018
Journal
Volume
8
Issue
1
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