Differences in mortality between infections due to extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae and Escherichia coli.

Published on Jul 2, 2018in Infection Control and Hospital Epidemiology2.938
· DOI :10.1017/ICE.2018.142
Jason P. Burnham6
Estimated H-index: 6
(WashU: Washington University in St. Louis),
Jennie H. Kwon11
Estimated H-index: 11
(WashU: Washington University in St. Louis)
+ 2 AuthorsMarin H. Kollef130
Estimated H-index: 130
(WashU: Washington University in St. Louis)
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Abstract
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#1Oded Scheuerman (Tel Aviv Sourasky Medical Center)H-Index: 1
#2Vered Schechner (Tel Aviv Sourasky Medical Center)H-Index: 16
Last. Jesús Rodríguez-BañoH-Index: 73
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OBJECTIVE: To compare the epidemiology, clinical characteristics, and mortality of patients with bloodstream infections (BSI) caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (ESBL-EC) versus ESBL-producing Klebsiella pneumoniae (ESBL-KP) and to examine the differences in clinical characteristics and outcome between BSIs caused by isolates with CTX-M versus other ESBL genotypes METHODS: As part of the INCREMENT project, 33 tertiary hospitals in 12 countries retrospective...
24 CitationsSource
#1Jason P. Burnham (WashU: Washington University in St. Louis)H-Index: 6
#2Margaret A. Olsen (WashU: Washington University in St. Louis)H-Index: 37
Last. Marin H. Kollef (WashU: Washington University in St. Louis)H-Index: 130
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Background: Multidrug-resistant organism (MDRO) infections are associated with high mortality and readmission rates. Infectious diseases (ID) consultation improves clinical outcomes for drug-resistant Staphylococcus aureus bloodstream infections. Our goal was to determine the association between ID consultation and mortality following various MDRO infections. Methods: This study was conducted with a retrospective cohort (January 1, 2006-October 1, 2015) at an academic tertiary referral center. W...
45 CitationsSource
#1Jason P. Burnham (WashU: Washington University in St. Louis)H-Index: 8
#2Jennie H. Kwon (WashU: Washington University in St. Louis)H-Index: 11
Last. Marin H. Kollef (WashU: Washington University in St. Louis)H-Index: 130
view all 5 authors...
OBJECTIVE To determine incidence of and risk factors for readmissions with multidrug-resistant organism (MDRO) infections among patients with previous MDRO infection. DESIGN Retrospective cohort of patients admitted between January 1, 2006, and October 1, 2015. SETTING Barnes-Jewish Hospital, a 1,250-bed academic tertiary referral center in St Louis, Missouri. METHODS We identified patients with MDROs obtained from the bloodstream, bronchoalveolar lavage (BAL)/bronchial wash, or other sterile si...
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#1Luisa A. Denkel (Humboldt University of Berlin)H-Index: 2
#2Friederike Maechler (Humboldt University of Berlin)H-Index: 1
Last. Rasmus Leistner (Humboldt University of Berlin)H-Index: 3
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Abstract Objectives Infections due to extended-spectrum beta-lactamase-producing Enterobacterales (ESBL-E) are considered infections with a high public health burden. In this study, we aimed to identify incidences of and risk factors for healthcare-associated infections (HAI) after rectal colonisation with ESBL-producing Escherichia coli (ESBL-EC) or Klebsiella pneumoniae (ESBL-KP). Methods This prospective cohort study was performed in 2014 and 2015. Patients colonised with ESBL-EC or ESBL-KP w...
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