Fresh Fruit Juice of Opuntia dillenii Haw. Attenuates Acetic Acid-Induced Ulcerative Colitis in Rats.

Published on Jan 1, 2019in Journal of Dietary Supplements
· DOI :10.1080/19390211.2018.1470128
S. Babitha1
Estimated H-index: 1
,
K. Bindu1
Estimated H-index: 1
+ 1 AuthorsV. P. Veerapur1
Estimated H-index: 1
Sources
Abstract
ABSTRACTThe present study aimed to evaluate the protective effect of fresh fruit juice of Opuntia dillenii Haw. (FJOD) on acetic acid–induced ulcerative colitis in rats. Fresh FJOD (2.5 and 5 ml/kg...
📖 Papers frequently viewed together
6 Citations
2 Citations
References30
Newest
#1Renata M. Martinez (UEL: Universidade Estadual de Londrina)H-Index: 16
#2Daniela T. Longhi-Balbinot (UEL: Universidade Estadual de Londrina)H-Index: 4
Last. Rubia Casagrande (UEL: Universidade Estadual de Londrina)H-Index: 33
view all 9 authors...
We have recently developed betalain-rich beetroot (Beta vulgaris) dye (betalain) to be used in food products. Betalain (30–300 mg/kg) intraperitoneal (i.p.) treatment diminished carrageenan (100 µg/paw)-induced paw edema and neutrophil migration to the paw skin tissue. Betalain (100 mg/kg) treatment by subcutaneous or per oral routes also inhibited the carrageenan-induced paw edema. Importantly, the post-treatment with betalain (100 mg/kg, i.p.) significantly inhibited carrageenan- and complete ...
35 CitationsSource
#1Pedro J. Vidal (University of Murcia)H-Index: 1
#2José Manuel López-Nicolás (University of Murcia)H-Index: 24
Last. Francisco García-Carmona (University of Murcia)H-Index: 62
view all 4 authors...
Abstract Betalains are natural pigments characteristic of plants of the order Caryophyllales. In this work, the role of betalains in the anti-inflammatory activity described for plant extracts is analysed in terms of the inactivation of the enzymes involved in the biochemical response (lipoxygenase and cyclooxygenase). Pure natural betalains and semi-synthetic analogues are demonstrated to promote a significant reduction of the enzymes activity. Reactions were followed spectrophotometrically and...
46 CitationsSource
#1Young-Hee Pyo (Sungshin Women's University)H-Index: 9
#2Yoo-Jeong Jin (Sungshin Women's University)H-Index: 2
Last. Ji-Young Hwang (Sungshin Women's University)H-Index: 3
view all 3 authors...
Four Korean kernel fruit (apple, pear, persimmon, and mandarin orange) juices were obtained by household processing techniques (i.e., blending, juicing). Whole and flesh fractions of each fruit were extracted by a blender or a juicer and then examined for phytochemical content (i.e., organic acids, polyphenol compounds). The antioxidant capacity of each juice was determined by ferric reducing antioxidant power (FRAP) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) assays. Results revealed that juices t...
14 CitationsSource
#1Dilip Dodda (Kakatiya University)H-Index: 4
#2Ruchi ChhajedH-Index: 2
Last. Jitendriya Mishra (Panjab University, Chandigarh)H-Index: 13
view all 3 authors...
Abstract Background Inflammatory bowel disease (IBD) is characterized by most common symptoms such as rectal bleeding. Lack of specific, curative treatments tempted us to evaluate the therapeutic efficacy of quercetin against acetic acid induced IBD like symptoms. Methods Animals were randomly divided into five groups ( n = 6): naive, control, sulphasalazine and quercetin, and were pretreated for three days. Colitis was induced by intra-rectal administration of 3% acetic acid. Results Pretreatme...
36 CitationsSource
#1Patrícia Rodrigues Orsi (UNESP: Sao Paulo State University)H-Index: 4
#2Leonardo Noboru Seito (UNESP: Sao Paulo State University)H-Index: 12
Last. Luiz Claudio Di Stasi (UNESP: Sao Paulo State University)H-Index: 21
view all 3 authors...
Abstract Ethnopharmacological relevance Stem bark and fruit pulp of Hymenaea stigonocarpa Mart ex. Hayne (Fabaceae) has been popularly used to treat inflammation and gastrointestinal diseases including ulcers, diarrhea and gastric pain. The aim of this study was to investigate the intestinal anti-inflammatory activity of a methanol extract derived from the stem bark and diet with fruit pulp of Hymenaea stigonocarpa in the TNBS model of intestinal inflammation in rats. Material and methods The in...
25 CitationsSource
#1Lucilene Patrícia Mazzolin (UNESP: Sao Paulo State University)H-Index: 3
#2Luiz Ricardo de Almeida Kiguti (UNESP: Sao Paulo State University)H-Index: 11
Last. Clélia Akiko Hiruma-Lima (UNESP: Sao Paulo State University)H-Index: 42
view all 9 authors...
Abstract Ethnopharmacological relevance An ethnopharmacological survey indicated that the bark from Qualea parviflora Mart. (Vochysiaceae) could be used to treat gastrointestinal disorders, such as diarrhea and intestinal inflammation. The objective of this study was to evaluate the effects of a methanolic extract from the bark of Qualea parviflora (QP) in an experimental model of diarrhea and intestinal inflammation induced in rodents. Material and methods The antidiarrheal and antispasmodic ef...
12 CitationsSource
#1Swarnamoni Das (Assam Medical College)H-Index: 9
#2Lalit Kanodia (Apollo Hospitals)H-Index: 1
Last. Abdul Hakim (Assam Medical College)H-Index: 1
view all 4 authors...
Objectives: To evaluate the effect of ethanolic extract of leaves of Paederia foetida on acetic acid induced colitis in albino rats. Materials and Methods: Ethanolic extract of Paederia foetida (EEPF) was prepared by percolation method. Acute toxicity test was done by using Organization for Economic Cooperation and Development guidelines. Albino rats were divided into four groups of five animals each. Groups A and B received 3% gum acacia. Groups C and D received EEPF 500 mg/kg body weight (BW) ...
10 CitationsSource
#1Longyan Zhao (ZNU: Zhanjiang Normal University)H-Index: 12
#2Wei Huang (HAU: Hunan Agricultural University)H-Index: 1
Last. Fuhua Zeng (ZNU: Zhanjiang Normal University)H-Index: 5
view all 7 authors...
Abstract The antihyperlipidaemic effects of ODP-Ia, one of the main components of Opuntia dillenii Haw. polysaccharides, were studied. Gavage administration of ODP-Ia was observed to significantly decrease serum lipid levels and to increase serum high-density lipoprotein cholesterol level in hyperlipidaemic rats. Similar suppressive patterns were also seen in hepatic total cholesterol and triglyceride levels. Moreover, the ODP-Ia administration significantly increased serum lecithin:cholesterol ...
59 CitationsSource
#1Azadeh Motavallian-Naeini (IUMS: Isfahan University of Medical Sciences)H-Index: 2
#2Sasan AndalibH-Index: 12
Last. Mohsen Minaiyan (IUMS: Isfahan University of Medical Sciences)H-Index: 24
view all 6 authors...
Trinitrobenzene sulfonic acid (TNBS)-induced colitis is one of the most common methods for studying inflammatory bowel disease in animal models. Several factors may, however, affect its reproducibility, rate of animal mortality, and macroscopic and histopathological outcomes. Our aim was to validate the main contributing factors to this method and compare the effects of different reference drugs upon remission of resultant colon injuries. TNBS was dissolved in 0.25 ml of ethanol (50% v/v) and in...
28 Citations
#1Aline Witaicenis (UNESP: Sao Paulo State University)H-Index: 8
#2Ana Carolina Luchini (UNESP: Sao Paulo State University)H-Index: 4
Last. Luiz Claudio Di Stasi (UNESP: Sao Paulo State University)H-Index: 21
view all 8 authors...
Abstract The aim of the present study was to compare the effects of the 4-methylesculetin with those produced by prednisolone and sulphasalazine and to elucidate the mechanisms involved in its action. Colitis was induced in rat by instillation of trinitrobenzenesulphonic acid (TNBS). The colon damage was evaluated using macroscopic, microscopic and biochemical analysis. In addition, in vitro studies were performed to evaluate cytokine production in cell cultures using the murine macrophage cell ...
42 CitationsSource
Cited By4
Newest
The aim of this study was to evaluate the effects of glutamine supplementation or exercise on gastric emptying and intestinal inflammation in rats with ulcerative colitis (UC). Strength exercise consisted of jump training 4 × 10 repetitions/5 days a week/8 weeks with progressive overload. Endurance exercise consisted of swimming without overload for a period of 1 h a day/5 days a week/8 weeks. Another group (sedentary) of animals was supplemented with L-glutamine (1 g/kg of body weight) orally f...
Source
#1Gholamreza Bahrami (Kermanshah University of Medical Sciences)H-Index: 22
#2Hossein Malekshahi (Kermanshah University of Medical Sciences)H-Index: 1
Last. Razieh Hatami (Kermanshah University of Medical Sciences)H-Index: 2
view all 7 authors...
Ulcerative colitis (UC) is a chronic intestinal inflammation. Common clinical symptoms are weight loss, diarrhea, ulcers, and inflammation. Aloe vera (AV) has several medicinal properties including antioxidant, anti-inflammatory analgesic, and improvement of gastric and skin ulcers. This study aimed to investigate the protective and therapeutic effects of AV gel on acetic acid-induced UC in rats. UC was induced in 48 rats by injection of 4% acetic acid into the rectum. Protective and treatment g...
Source
#1Yadira Ramírez-Rodríguez (Instituto Potosino de Investigación Científica y Tecnológica)H-Index: 1
#2Miriam Martínez-Huélamo (University of Barcelona)H-Index: 20
Last. Joyce Trujillo (Instituto Potosino de Investigación Científica y Tecnológica)H-Index: 13
view all 6 authors...
Abstract The Mexican drylands possess enormous biotic and cultural wealth, representing 65% of the national territory. Approximately 50% of Mexican dryland flora is endemic and accompanied by ample local and traditional knowledge. There are certain types of cactus fruits that are being technologically produced. However, there are other cactus fruit that are underutilized and understudied that could be promoted for their sustainable use. Evidence indicates that the genera of Escontria, Myrtilocac...
5 CitationsSource
#1Paloma Oliveira Antonino de Assis (UFPB: Federal University of Paraíba)H-Index: 5
#2Gerlane Coelho Bernardo Guerra (UFRN: Federal University of Rio Grande do Norte)H-Index: 14
Last. Rita de Cássia Ramos do Egypto Queiroga (UFPB: Federal University of Paraíba)H-Index: 21
view all 13 authors...
Inflammatory bowel disease (IBD) is characterized by severe mucosal damage in the intestine and a deregulated immune response. Natural products derived from plants that are rich in bioactive compounds are used by many patients with IBD. Xique–xique (Pilosocereus gounellei) is a cactus of the Caatinga family that has been used by the local population for food and medicinal purposes. The intestinal anti-inflammatory effect of xique–xique cladode juice was evaluated in the present study. A dose of ...
6 CitationsSource