Oxidative stress-induced skeletal muscle injury involves in NF-κB/p53-activated immunosuppression and apoptosis response in copper (II) or/and arsenite-exposed chicken

The adverse effects of environmental toxicants such as copper and arsenic occur due to the generation of reactive oxygen species. Recent study also reported that both copper (Cu) and arsenic (As) may alter muscle regeneration. In order to assess the toxic effects of copper and arsenic on chicken skeletal muscle, chickens were subjected by different toxicologically relevant concentrations of copper or arsenic and their combination in diets for 12...