Review paper

Toward an Ensemble View of Chromatosome Structure: A Paradigm Shift from One to Many

Volume: 26, Issue: 8, Pages: 1050 - 1057
Published: Aug 1, 2018
Abstract
There is renewed interest in linker histone (LH)-nucleosome binding and how LHs influence eukaryotic DNA compaction. For a long time, the goal was to uncover "the structure of the chromatosome," but recent studies of LH-nucleosome complexes have revealed an ensemble of structures. Notably, the reconstituted LH-nucleosome complexes used in experiments rarely correspond to the sequence combinations present in organisms. For a full understanding of...
Paper Details
Title
Toward an Ensemble View of Chromatosome Structure: A Paradigm Shift from One to Many
Published Date
Aug 1, 2018
Journal
Volume
26
Issue
8
Pages
1050 - 1057
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