Glycomic and Proteomic Changes in Aging Brain Nigrostriatal Pathway
Abstract
Parkinson's disease (PD) is a neurological disorder characterized by the progressive loss of functional dopaminergic neurons in the nigrostriatal pathway in the brain. Although current treatments provide only symptomatic relief, gene therapy has the potential to slow or halt the degeneration of nigrostriatal dopamine neurons in PD patients. Adeno-associated viruses (AAV) are vectors of choice in gene therapy because of their well-characterized...
Paper Details
Title
Glycomic and Proteomic Changes in Aging Brain Nigrostriatal Pathway
Published Date
Sep 1, 2018
Volume
17
Issue
9
Pages
1778 - 1787
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