Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant
Abstract
Metal-based nanoparticles (NPs) stimulate innate immunity; however, they have never been demonstrated to be capable of aiding the generation of specific cellular immune responses. Therefore, our objective was to evaluate whether iron oxide-based NPs have adjuvant properties in generating cellular Th1, Th17 and TCD8 (Tc1) immune responses. For this purpose, a fusion protein (CMX) composed of Mycobacterium tuberculosis antigens was used as a...
Paper Details
Title
Specific T cell induction using iron oxide based nanoparticles as subunit vaccine adjuvant
Published Date
Jun 18, 2018
Pages
1 - 16
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