Global pairwise RNA interaction landscapes reveal core features of protein recognition
Abstract
RNA-protein interactions permeate biology. Transcription, translation, and splicing all hinge on the recognition of structured RNA elements by RNA-binding proteins. Models of RNA-protein interactions are generally limited to short linear motifs and structures because of the vast sequence sampling required to access longer elements. Here, we develop an integrated approach that calculates global pairwise interaction scores from in vitro selection...
Paper Details
Title
Global pairwise RNA interaction landscapes reveal core features of protein recognition
Published Date
Jun 28, 2018
Journal
Volume
9
Issue
1
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