miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells

Volume: 26, Issue: 1-2, Pages: 1 - 10
Published: Jun 21, 2018
Abstract
It has been found that microRNAs (miRNAs) play a key role in drug resistance. The purpose of the current study was to investigate the function of miR-182 in trastuzumab resistance in breast cancer cells. The results showed that both breast cancer SKBR3 trastuzumab-resistant cells (SKBR3/TR) and BT474 trastuzumab-resistant cells (BT474/TR) were associated with miR-182 downregulation compared with their parental cells. Ectopic expression of the...
Paper Details
Title
miR-182 regulates trastuzumab resistance by targeting MET in breast cancer cells
Published Date
Jun 21, 2018
Volume
26
Issue
1-2
Pages
1 - 10
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