SAT0011 Mertk+ monocytes are expanded in the peripheral blood of patients with active igg4-related disease and infiltrate affected organs

Background

IgG4-Related Disease (IgG4-RD) is a multi-organ fibro-inflammatory disorder characterised by tumefactive lesions with well-defined histological features including lymphoplasmacitic infiltrate rich in IgG4⁺ plasma cells, storiform fibrosis and obliterative phlebitis¹. Alternatively-activated macrophages (M2) have also been reported to abundantly infiltrate IgG4-RD lesions, but their role in IgG4-RD...