Endoplasmic reticulum stress in ischemic and nephrotoxic acute kidney injury.
Abstract
Acute kidney injury (AKI) is a medical condition characterized by kidney damage with a rapid decline of renal function, which is associated with high mortality and morbidity. Recent research has further established an intimate relationship between AKI and chronic kidney disease. Perturbations of kidney cells in AKI result in the accumulation of unfolded and misfolded proteins in the endoplasmic reticulum (ER), leading to unfolded protein...
Paper Details
Title
Endoplasmic reticulum stress in ischemic and nephrotoxic acute kidney injury.
Published Date
Jul 11, 2018
Journal
Volume
50
Issue
5
Pages
381 - 390
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Notes
History