Probing Plasmodium falciparum sexual commitment at the single-cell level

Nicolas M. B. Brancucci; Mariana De Niz; Timothy J. Straub; Deepali Ravel; Lauriane Sollelis; Bruce W. Birren; Till S. Voss; Daniel E. Neafsey; Matthias Marti

doi:https://doi.org/10.12688/wellcomeopenres.14645.4

doi.org/10.12688/wellcomeopenres.14645.4

Probing Plasmodium falciparum sexual commitment at the single-cell level

Nicolas M. B. Brancucci

17

,

Mariana De Niz

16

,

..., Matthias Marti

42

Wellcome open research

Volume: 3, Pages: 70 - 70

Published: Oct 17, 2018

Abstract

Background: Malaria parasites go through major transitions during their complex life cycle, yet the underlying differentiation pathways remain obscure. Here we apply single cell transcriptomics to unravel the program inducing sexual differentiation in Plasmodium falciparum. Parasites have to make this essential life-cycle decision in preparation for human-to-mosquito...

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Paper Details

Title

Probing Plasmodium falciparum sexual commitment at the single-cell level

DOI

doi.org/10.12688/wellcomeopenres.14645.4

Published Date

Oct 17, 2018

Journal

Wellcome open research

Volume

3

Pages

70 - 70

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