Stachydrine suppresses viability & migration of astrocytoma cells via CXCR4/ERK & CXCR4/Akt pathway activity

Volume: 14, Issue: 15, Pages: 1443 - 1459
Published: Jun 1, 2018
Abstract
Aim: Pilocytic astrocytomas (PAs) are a common adolescent malignancy. We evaluated the effects of the betaine stachydrine on human PA cells as well as its associated molecular mechanism(s). Materials & methods: Various experiments assessing stachydrine's effects on the human PA cell line Res186 were performed. Results & conclusion: Stachydrine dose-dependently suppressed proliferation and colony formation in Res186 cells with no such...
Paper Details
Title
Stachydrine suppresses viability & migration of astrocytoma cells via CXCR4/ERK & CXCR4/Akt pathway activity
Published Date
Jun 1, 2018
Volume
14
Issue
15
Pages
1443 - 1459
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