The significance, trafficking and determination of labile iron in cytosol, mitochondria and lysosomes

Volume: 10, Issue: 7, Pages: 899 - 916
Published: Jan 1, 2018
Abstract
The labile iron pool (LIP) is a pool of chelatable and redox-active iron, not only essential for a wide variety of metabolic process, but also as a catalyst in the Fenton reaction, causing the release of hazardous reactive oxygen species (ROS) with potential for inducing oxidative stress and cell damage. The cellular LIP represents the entirety of every heterogenous sub-pool of iron, not only present in the cytosol, but also in mitochondria,...
Paper Details
Title
The significance, trafficking and determination of labile iron in cytosol, mitochondria and lysosomes
Published Date
Jan 1, 2018
Volume
10
Issue
7
Pages
899 - 916
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