An uncertainty metric to evaluate deformation vector fields for dose accumulation in radiotherapy

Background and purposeIn adaptive radiotherapy, deformable image registration (DIR) is used to propagate delineations of tumors and organs into a new therapy plan and to calculate the accumulated total dose. Many DIR accuracy metrics have been proposed. An alternative proposed here could be a local uncertainty (LU) metric for DIR results.Materials and methodsThe LU represented the uncertainty of each DIR position and was focused on deformation...