Long-Term Cancer Specific Anxiety in Men Undergoing Active Surveillance of Prostate Cancer: Findings from a Large Prospective Cohort

Published on Jun 7, 2018in The Journal of Urology5.925
· DOI :10.1016/J.JURO.2018.06.013
Karim Marzouk5
Estimated H-index: 5
(MSK: Memorial Sloan Kettering Cancer Center),
Melissa Assel19
Estimated H-index: 19
(MSK: Memorial Sloan Kettering Cancer Center)
+ 1 AuthorsAndrew J. Vickers125
Estimated H-index: 125
(MSK: Memorial Sloan Kettering Cancer Center)
Purpose: Active surveillance is the preferred management of low risk prostate cancer. Cancer specific anxiety during active surveillance remains under studied. We evaluated long-term anxiety in men on active surveillance to determine whether interventions must be tailored to improve adherence.Materials and Methods: A total of 413 men enrolled in active surveillance at a single tertiary care center completed quality of life surveys as part of routine care. A modified version of the MAX-PC (Memorial Anxiety Scale for Prostate Cancer) was used to determine cancer specific anxiety. Generalized estimating equations were applied to evaluate the association between anxiety and the duration on surveillance. Additionally, we examined associations between anxiety and patient age, marital status, Gleason score, the number of positive cores, family history and overall health.Results: Median patient age was 61 years, median prostate specific antigen at diagnosis was 4.4 ng/ml and 95% of the patients had Gleason 6 dise...
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