Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer
Abstract
Background The recurrence score based on the 21-gene breast cancer assay predicts chemotherapy benefit if it is high and a low risk of recurrence in the absence of chemotherapy if it is low; however, there is uncertainty about the benefit of chemotherapy for most patients, who have a midrange score. Methods We performed a prospective trial involving 10,273 women with hormone-receptor–positive, human epidermal growth factor receptor 2...
Paper Details
Title
Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer
Published Date
Jun 3, 2018
Volume
379
Issue
2
Pages
111 - 121
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