Gender-related differences in pharmacokinetics, tissue distribution, and excretion of 20(R)-25-methoxyl-dammarane-3β,12β,20-triol and its metabolite in rats and anti-ovarian cancer evaluation.

Volume: 158, Pages: 327 - 338
Published: Sep 5, 2018
Abstract
null null Our previous study suggests a well-defined pharmacological activity of 20(R)-25-methoxyl-dammarane-3β,12β,20-triol (AD-1) and its metabolite 20(R)-dammarane-3β,12β,20,25-tetrol (AD-2). The current study aims to investigate the gender-related differences in pharmacokinetics, tissue distribution, and excretion of AD-1 and its metabolite in both male and female rats. A sensitive and rapid ultra-performance liquid chromatography tandem...
Paper Details
Title
Gender-related differences in pharmacokinetics, tissue distribution, and excretion of 20(R)-25-methoxyl-dammarane-3β,12β,20-triol and its metabolite in rats and anti-ovarian cancer evaluation.
Published Date
Sep 5, 2018
Volume
158
Pages
327 - 338
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