Internal medicine

Cohort study

Antibiotics

Biology

Microbiology

Logistic regression

Odds ratio

Prospective cohort study

Septic shock

Intensive care unit

Sepsis

Bacteremia

Blood culture

Cohort

Medicine

Clinical Microbiology and Infection

Sepsis guidelines recommend obtaining blood cultures before starting anti-infective therapy in patients with sepsis. However, little is known of how antibiotic treatment before sampling affects bacterial growth. The aim of this study was to compare the results of blood cultures drawn before and during antibiotic therapy.

Impact of antibiotic administration on blood culture positivity at the beginning of sepsis: a prospective clinical cohort study