Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations
Abstract
Despite the remarkable advances in the early diagnosis and treatment, overall 5-year survival rate of patients with pancreatic cancer is less than 10%. Gemcitabine (GEM), a cytidine nucleoside analogue and ribonucleotide reductase inhibitor, is a primary option for patients with advanced pancreatic cancer; however, its clinical efficacy is extremely limited. This unfavorable clinical outcome of pancreatic cancer patients is at least in part...
Paper Details
Title
Impact of RUNX2 on drug-resistant human pancreatic cancer cells with p53 mutations
Published Date
Mar 20, 2018
Journal
Volume
18
Issue
1
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