Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
Abstract
Epigenetics contributes to the pathogenesis of immune-mediated diseases like rheumatoid arthritis (RA). Here we show the first comprehensive epigenomic characterization of RA fibroblast-like synoviocytes (FLS), including histone modifications (H3K27ac, H3K4me1, H3K4me3, H3K36me3, H3K27me3, and H3K9me3), open chromatin, RNA expression and whole-genome DNA methylation. To address complex multidimensional relationship and reveal epigenetic...
Paper Details
Title
Comprehensive epigenetic landscape of rheumatoid arthritis fibroblast-like synoviocytes
Published Date
May 15, 2018
Journal
Volume
9
Issue
1
Pages
1921 - 1921
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