On the Stability of DNA Origami Nanostructures in Low‐Magnesium Buffers
Abstract
DNA origami structures have great potential as functional platforms in various biomedical applications. Many applications, however, are incompatible with the high Mg2+ concentrations commonly believed to be a prerequisite for maintaining DNA origami integrity. Herein, we investigate DNA origami stability in low-Mg2+ buffers. DNA origami stability is found to crucially depend on the availability of residual Mg2+ ions for screening electrostatic...
Paper Details
Title
On the Stability of DNA Origami Nanostructures in Low‐Magnesium Buffers
Published Date
Jul 20, 2018
Journal
Volume
57
Issue
30
Pages
9470 - 9474
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