On the Stability of DNA Origami Nanostructures in Low‐Magnesium Buffers

Volume: 57, Issue: 30, Pages: 9470 - 9474
Published: Jul 20, 2018
Abstract
DNA origami structures have great potential as functional platforms in various biomedical applications. Many applications, however, are incompatible with the high Mg2+ concentrations commonly believed to be a prerequisite for maintaining DNA origami integrity. Herein, we investigate DNA origami stability in low-Mg2+ buffers. DNA origami stability is found to crucially depend on the availability of residual Mg2+ ions for screening electrostatic...
Paper Details
Title
On the Stability of DNA Origami Nanostructures in Low‐Magnesium Buffers
Published Date
Jul 20, 2018
Volume
57
Issue
30
Pages
9470 - 9474
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