Single-Molecule Imaging of mRNA Localization and Regulation during the Integrated Stress Response
Abstract
Biological phase transitions form membrane-less organelles that generate distinct cellular environments. How molecules are partitioned between these compartments and the surrounding cellular space and the functional consequence of this localization is not well understood. Here, we report the localization of mRNA to stress granules (SGs) and processing bodies (PBs) and its effect on translation and degradation during the integrated stress...
Paper Details
Title
Single-Molecule Imaging of mRNA Localization and Regulation during the Integrated Stress Response
Published Date
Mar 1, 2019
Journal
Volume
73
Issue
5
Pages
946 - 958.e7
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