Immunogenic effects of chemotherapy-induced tumor cell death.
Abstract
Emerging evidence suggests that the clinical success of conventional chemotherapy is not solely attributed to tumor cell toxicity, but also results from the restoration of immunosurveillance, which has been largely neglected in the past preclinical and clinical research. Antitumor immune response can be primed by immunogenic cell death (ICD), a type of cell death characterized by cell-surface translocation of calreticulin (CRT), extracellular...
Paper Details
Title
Immunogenic effects of chemotherapy-induced tumor cell death.
Published Date
May 17, 2018
Journal
Volume
5
Issue
3
Pages
194 - 203
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Notes
History