γδTCR regulates production of interleukin-27 by neutrophils and attenuates inflammatory arthritis
Abstract
γδ T cells have been implicated in inflammatory diseases as an important link between the innate and adaptive immune responses, however, their role in inflammatory arthritis remain unclear. To define the contribution of γδ T cells in the pathogenesis of inflammatory arthritis, we performed gene transfer of IL-23 in B10.RIII mice to establish joint inflammation in the presence or absence of γδ T cells. We demonstrated that γδ T cell blockade has...
Paper Details
Title
γδTCR regulates production of interleukin-27 by neutrophils and attenuates inflammatory arthritis
Published Date
May 15, 2018
Journal
Volume
8
Issue
1
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