Convergence of placenta biology and genetic risk for schizophrenia
Abstract
Defining the environmental context in which genes enhance disease susceptibility can provide insight into the pathogenesis of complex disorders. We report that the intra-uterine environment modulates the association of schizophrenia with genomic risk (in this study, genome-wide association study–derived polygenic risk scores (PRSs)). In independent samples from the United States, Italy, and Germany, the liability of schizophrenia explained by...
Paper Details
Title
Convergence of placenta biology and genetic risk for schizophrenia
Published Date
May 28, 2018
Journal
Volume
24
Issue
6
Pages
792 - 801
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History