Phosphocreatine-modified chitosan porous scaffolds promote mineralization and osteogenesis in vitro and in vivo
Abstract
By mimicking the role of phosphate groups in native tissues and encouraging tissue formation, phosphate-functionalized biopolymers have been widely employed to accelerate the formation of bone injury. In this study, phosphocreatine is screened as a phosphate source and applied in the preparation of phosphocreatine-modified chitosan (CS-P) and porous scaffolds. CS-P exhibits much better hydrophilicity, solubility, protein adsorption and...
Paper Details
Title
Phosphocreatine-modified chitosan porous scaffolds promote mineralization and osteogenesis in vitro and in vivo
Published Date
Sep 1, 2018
Journal
Volume
12
Pages
21 - 33
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