Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems
Abstract
In the past 15 years, impressive progress has been made to understand the molecular mechanism behind aneuploidy, largely due to the effort of using various -omics approaches to study model systems (e.g. yeast and mouse models) and patient samples, as well as the new realization that chromosome alteration-mediated genome instability plays the key role in cancer. As the molecular characterization of the causes and effects of aneuploidy progresses,...
Paper Details
Title
Understanding aneuploidy in cancer through the lens of system inheritance, fuzzy inheritance and emergence of new genome systems
Published Date
May 10, 2018
Journal
Volume
11
Issue
1
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