Robust motion correction in CEST imaging exploiting low‐rank approximation of the z‐spectrum

To introduce and evaluate an image registration technique for robust quantification of CEST acquisitions corrupted by motion.The proposed iterative algorithm exploits a low-rank approximation of the z-spectrum (LRAZ), to gradually separate the contrast variation due to saturation at different off-resonance frequencies and accompanying motion. This registration method was first tested in a creatine CEST analysis of a phantom with simulated rigid...