Refractory (planetary science)

Pouchitis

Ulcerative colitis

Anastomosis

Astrobiology

Inflammatory bowel disease

Pouch

Familial adenomatous polyposis

Complication

Gastroenterology

Disease

Biology

Cancer

Proctocolectomy

Internal medicine

Colorectal cancer

Surgery

Medicine

Inflammatory Bowel Diseases

Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) has become the preferred surgical treatment for refractory or complicated ulcerative colitis (UC) and familial adenomatous polyposis (FAP). Pouchitis is the most common complication of this procedure and can occur in about 50% of patients. Treatment of pouchitis depends on the phenotype of disease. Pouchitis can be classified as acute, chronic/refractory, or secondary pouchitis, which includes pouchitis occurring due to Crohn's disease (CD). CD of the pouch is becoming an increasingly recognized problem, and management is challenging. This article reviews the literature and offers treatment recommendations regarding management of pouchitis and CD of the pouch.

Management of Pouchitis and Other Common Complications of the Pouch