N-Terminal pro-Brain Natriuretic Peptide and Associations With Brain Magnetic Resonance Imaging (MRI) Features in Middle Age: The CARDIA Brain MRI Study

Objective As a part of research on the heart-brain axis, we investigated the association of N-terminal pro-Brain Natriuretic Peptide (NT-proBNP) with brain structure and function in a community-based cohort of middle-aged adults from the Brain MRI sub-study of the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Approach and Results In a cohort of 634 community-dwelling adults with a mean (range) age of 50.4 (46-52) years, we...