Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity.
Abstract
Acetaminophen (APAP) toxicity is the most common cause of acute liver failure and a major indication for liver transplantion in the United States and Europe. Although significant progress has been made in understanding the molecular mechanisms underlying APAP hepatotoxicity, there is still an urgent need to find novel and effective therapies against APAP-induced acute liver failure. Hepatic APAP metabolism results in the production of the...
Paper Details
Title
Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity.
Published Date
May 15, 2018
Journal
Volume
9
Pages
453 - 453
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Notes
History