3D biomaterial matrix to support long term, full thickness, immuno-competent human skin equivalents with nervous system components

Volume: 198, Pages: 194 - 203
Published: Apr 1, 2019
Abstract
Current commercially available human skin equivalents (HSEs) are used for relatively short term studies (∼1 week) due in part to the time-dependent contraction of the collagen gel-based matrix and the limited cell types and skin tissue components utilized. In contrast, here we describe a new matrix consisting of a silk-collagen composite system that provides long term, stable cultivation with reduced contraction and degradation over time. This...
Paper Details
Title
3D biomaterial matrix to support long term, full thickness, immuno-competent human skin equivalents with nervous system components
Published Date
Apr 1, 2019
Volume
198
Pages
194 - 203
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