Targeted Therapies for Autosomal Dominant Polycystic Kidney Disease
Abstract
Background: Autosomal dominant polycystic kidney disease (ADPKD) is the most common life-threatening genetic disease in humans, affecting approximately 1 in 500 people. ADPKD is characterized by cyst growth in the kidney leading to progressive parenchymal damage and is the underlying pathology in approximately 10% of patients requiring hemodialysis or transplantation for end-stage kidney disease. The two proteins that are mutated in ADPKD,...
Paper Details
Title
Targeted Therapies for Autosomal Dominant Polycystic Kidney Disease
Published Date
Aug 27, 2019
Journal
Volume
26
Issue
17
Pages
3081 - 3102
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