Pharmacokinetics of lipid-drug conjugates loaded into liposomes

Volume: 128, Pages: 188 - 199
Published: Jul 1, 2018
Abstract
Drugs that are neither lipophilic nor suitable for encapsulation via remote loading procedures are generally characterized by low entrapment efficiencies and poor retention in liposomes. One approach to circumvent this problem consists in covalently linking a lipid to the drug molecule in order to permit its insertion into the vesicle membrane. The nature of the conjugated lipid and linker, as well as the composition of the liposomal bilayer...
Paper Details
Title
Pharmacokinetics of lipid-drug conjugates loaded into liposomes
Published Date
Jul 1, 2018
Volume
128
Pages
188 - 199
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