Stromal interaction molecule 1 modulates blood pressure via NO production in vascular endothelial cells
Abstract
In vascular endothelial cells, store-operated calcium entry (SOCE) activates endothelial NO synthase (eNOS) and regulates nitric oxide (NO) production as well as flow-dependent mechanical stimuli. Stromal interaction molecule 1, or STIM1, was recently identified to be essential for SOCE, acting as a calcium sensor for intracellular calcium stores. However, how STIM1 affects endothelial function and blood pressure (BP) remains unclear. We...
Paper Details
Title
Stromal interaction molecule 1 modulates blood pressure via NO production in vascular endothelial cells
Published Date
Apr 25, 2018
Journal
Volume
41
Issue
7
Pages
506 - 514
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