Goodpasture's autoimmune disease — A collagen IV disorder

Volume: 71-72, Pages: 240 - 249
Published: Oct 1, 2018
Abstract
Goodpasture's (GP) disease is an autoimmune disorder characterized by the deposition of pathogenic autoantibodies in basement membranes of kidney and lung eliciting rapidly progressive glomerulonephritis and pulmonary hemorrhage. The principal autoantigen is the α345 network of collagen IV, which expression is restricted to target tissues. Recent discoveries include a key role of chloride and bromide for network assembly, a novel...
Paper Details
Title
Goodpasture's autoimmune disease — A collagen IV disorder
Published Date
Oct 1, 2018
Volume
71-72
Pages
240 - 249
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